Evaluation of Median Lethal Dose and Subchronic Oral Toxicity Assessment of Ethanolic Leaf Extract of Phyllanthus amarus
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چکیده
منابع مشابه
Hypoglycemic activity of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice
Phyllanthus amarus is an indigenous medicinal plant, with a folk reputation as hypoglycemic agent in Central and Southern India. In the present investigation hypoglycemic activity of ethanolic leaf extract of Phyllanthus amarus was evaluated using alloxan induced hyperglycemic mice. Blood glucose levels of all the mice of each group were tested before the treatments on fasting mice and then tes...
متن کاملAntidiabetic effect of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice
Phyllanthus amarus Schum. Thonn. is an indigenous medicinal plant, which has a folk reputation in central and southern India as hypoglycemic agent. The present investigation was carried out to evaluate the antidiabetic effect of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice. Blood glucose levels and body weights of control and diabetic mice were monitored. In the...
متن کاملAnalgesic activity of aqueous leaf extract of Phyllanthus amarus.
Various doses of the aqueous extract of Phyllanthus amarus (AEPA) were investigated for analgesic and anti-inflammatory activities using both thermal and chemical models of pain assessment in rats. The extract caused a significant (P < 0.05) dose related increase inhibition of the carrageenan-induced paw oedema in the rats. The inhibition produced by 200 mg/kg AEPA (70.20%) was significantly hi...
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This study was carried in order to determine short-term (acute) and long-term(subchronic) effects of Melastomastrum capitatum leaf methanol extract in the management and treatment of certain diseases in traditional and complementary medicines by many villages in Mambila Nigeria. Acute and subchronic toxicities were carried out in accordance with the Organization for Economic Cooperation and D...
متن کاملAcute toxicity studies of aqueous leaf extract of Phyllanthus niruri
Phyllanthus niruri is a plant with medicinal properties. It is often used to treat mild malaria and the elimination of renal stones. However, studies on its toxicity are scarce. The study was carried out to determine if the aqueous leaf extract of P. niruri administered to female Sprague-Dawley rats would illicit evidence of toxicity. Fifteen female rats weighing 150-200 g were divided into 3 g...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Research International
سال: 2019
ISSN: 2456-9119
DOI: 10.9734/jpri/2019/v26i430145